Cytogenetics
Cytogenetics
focuses on the study and analysis of chromosomes, their structure, and their abnormalities in relation to human genetics and diseases.
Cytogenetics testing is utilized to detect numerical and structural chromosome abnormalities in metaphase cells. HNL Lab Medicine’s state-of-the-art Cytogenetics laboratory provides the most advanced chromosome analysis for identifying and diagnosing genetic abnormalities. Chromosome and FISH testing help to identify the diagnosis, prognosis and monitoring of the treatment for oncologic malignancies. The identified tumor markers help in managing the targeted therapies and provide valuable pathologic information. Additionally, these techniques along with chromosome microarray are also useful in identifying the constitutional chromosome abnormalities for the congenital malformations, intellectual disability, and fertility or recurrent pregnancy loss.
Common Cytogenetic Test Methods
Chromosome Analysis
- Chromosome analysis for Peripheral blood (Constitutional) - Turnaround Time: 7 Days
- Chromosome analysis for Bone marrow/Leukemic Blood/Tissue (Oncology) - Turnaround Time: 10-14 Days
Chromosome Microarray
- Congenital postnatal disorders, developmental delay, Autism Spectrum Disorders - Turnaround Time: 14 Days
Constitutional Abnormalities FISH Probes, DiGeorge Syndrome, William Beuren Syndrome, SRY
- Turnaround Time: 3-5 Days
Myelodysplastic Syndrome (MDS) Panel
- Turnaround Time: 3-5 Days
Acute Myeloid Leukemia (AML) Panel
- Turnaround Time: 3-5 Days
Non-Hodgkin Lymphoma Panel
- Turnaround Time: 3-5 Days
T-Cell Lymphoma
- Turnaround Time: 3-5 Days
Chronic Myelogenous Leukemia (CML)
- Turnaround Time: 3-5 Days
Acute Promyelocytic Leukemia (APL)
- Turnaround Time: STAT-<24 hrs
Chronic Lymphocytic Leukemia (CLL)
- Turnaround Time: 3-5 Days
Breast cancer/Gastric Cancer
- Turnaround Time: 5-7 Days
B-Cell Lymphoma
- Turnaround Time: 5-7 Days
MetaSystems: AI-Driven Platform for Digital Karyotyping and FISH
HNL Cytogenetics uses MetaSystems, a platform for digital karyotyping and FISH with built in artificial intelligence (AI) to improve the quality and speed of diagnosis and prognosis of both cancer (hematological and solid tumors) and constitutional disorders. This platform reduces the time it takes to create a karyogram by over 95%, enabling our Cytogenetics team to provide answers faster. Through AI-enabled automation. MetaSystems not only helps to reduce the turnaround time, but also ensures consistent quality results for both FISH and chromosome analysis.
Additional Resources
