Automation in the Clinical Laboratory

Clinical laboratory automation is essential to deliver high quality results in the most cost effective and efficient way. Automation requires minimal operator intervention and helps to increase productivity, tracking of specimens within the laboratory, decreased turnaround times, improvements in specimen handling, improved laboratory safety, and minimizes errors.

LYME Disease

As you continue to spend more time outside enjoying the weather, you’ll be sharing your space with some critters you’ll want to be aware of. Deer ticks can carry the bacteria that causes Lyme disease, which can have a critical impact on your health if untreated.

HNL Lab Medicine Artwork Contest Celebrates Healthcare Heroes

Throughout the month of May, HNL Lab Medicine, a regional leader in high-quality, innovative laboratory medicine services, announced an artwork contest for children in grades K-8. The goal of this contest was to promote awareness of the healthcare field, encourage creativity, and include a valuable connection to the community in each of HNL’s patient service centers.

Shereen M.F. Gheith

MD, PhD

Chief, Section of Hematopathology Chief, Section of Molecular Pathology

Dr. Gheith received her medical degree from the Ain Shams University School of Medicine, Cairo, where she was also awarded a Master of Science degree in Clinical Pathology, and a PhD in Immunology. She completed both her pathology residency and hematopathology fellowship at the Hospital of the University of Pennsylvania, Philadelphia, Pa. Dr. Gheith is a Diplomate of the American Board of Pathology and is certified in combined Anatomic Pathology and Clinical Pathology, and also board certified in hematopathology. Dr. Shereen Gheith has an academic appointment as Associate Professor of Pathology on the Clinician Educator Pathway at University of South Florida (USF), Morsani College of Medicine.

Publications

Shereen Gheith MD, Chief, Section of Hematopathology & Clinical Laboratory Medicine and Dennis Cornfield, MD, Education Coordinator coauthored a publication entitled “ Promyelocytic sarcoma present with spinal cord compression and treated successfully with surgical debulking and the PETHEMA regimen for acute promyelocytic leukemia ”. Case Reports in Clinical Pathology. 2015; 2(3).

Shereen Gheith MD, Chief, Section of Hematopathology & Clinical Laboratory Medicine coauthored a publication entitled “Primary dural lymphoblastic B-cell lymphoma: a rare subtype of aggressive dural lymphoma”. J Hematopathol. 2015.

Immunoblastic follicular lymphoma: a very unusual transformation of low-grade follicular lymphoma.
Authors: Gheith S; Hematopathology Section, Department of Pathology, Health Network Laboratories/Lehigh Valley Health Network, Allentown, PA, 18103. Electronic address: Shereen_M.Gheith@lvhn.org. Cornfield D; Hematopathology Section, Department of Pathology, Health Network Laboratories/Lehigh Valley Health Network, Allentown, PA, 18103. Chen W; Molecular Diagnostics Section, Cancer Genetics, Rutherford, NJ, 07070. Singh-Kahlon P; Cytogenetics Section, Cancer Genetics, Rutherford, NJ, 07070.
Ahmed B; Hematology/Medical Oncology Section, Department of Medicine, Lehigh Valley Health Network, Allentown, PA, 18103.
Source: Human Pathology [Hum Pathol] 2014 Nov; Vol. 45 (11), pp. 2359-63. Date of Electronic Publication: 2014 Aug 13.

Transformation of the 5q- syndrome to acute lymphoblastic leukemia: a report of two cases and review of the literature.
Agostino NM, Ahmed B, Popescu D. Gheith S, Int J Clin Exp Pathol. 2011 Mar;4(3):322-6. Epub 2011 Mar 22. Review. PMID: 21487529 Free PMC Article

Percentage of {gamma}{delta} T cells in panniculitis by paraffin immunohistochemical analysis.
Roullet M, Gheith SM, Mauger J, Junkins-Hopkins JM, Choi JK. Am J Clin Pathol. 2009 Jun;131(6):820-6. doi: 10.1309/AJCPMG37MXKYPUBE. PMID: 19461088 Free Article

Small lymphocytic lymphoma/chronic lymphocytic leukemia in a pelvic myelolipoma.
Gheith S, Boulay R, Cornfield D. Int J Clin Exp Pathol. 2009;2(1):95-8. Epub 2008 Jan 31. PMID: 18830383 [PubMed] Free PMC Article

Flow cytometric quantitation of natural killer cells and T lymphocytes expressing T-cell receptors alpha/beta and gamma/delta is not helpful in distinguishing benign from malignant body cavity effusions.
Cornfield DB, Gheith SM. Cytometry B Clin Cytom. 2009 May;76(3):213-7. doi: 10.1002/cyto.b.20455. PMID: 18803280 Free Article

A third case of chronic eosinophilic leukemia with the (8;9)(p23;p24) translocation.
Cornfield DB, Gheith SM, Friedman EL. Cancer Genet Cytogenet. 2008 Aug;185(1):60-1. doi: 10.1016/j.cancergencyto.2008.04.018. No abstract available. PMID: 18656698

Adhesion- and degranulation-promoting adapter protein is required for efficient thymocyte development and selection.
Wu JN, Gheith S, Bezman NA, Liu QH, Fostel LV, Swanson AM, Freedman BD, Koretzky GA, Peterson EJ.
J Immunol. 2006 Jun 1;176(11):6681-9. PMID: 16709827 Free Article

PRAM-1 is required for optimal integrin-dependent neutrophil function.
Clemens RA, Newbrough SA, Chung EY, Gheith S, Singer AL, Koretzky GA, Peterson EJ.
Mol Cell Biol. 2004 Dec;24(24):10923-32. PMID: 15572693 Free PMC Article

Recruitment of SLP-76 to the membrane and glycolipid-enriched membrane microdomains replaces the requirement for linker for activation of T cells in T cell receptor signaling.
Boerth NJ, Sadler JJ, Bauer DE, Clements JL, Gheith SM, Koretzky GA. J Exp Med. 2000 Oct 2;192(7):1047-58.PMID:11015445 Free PMC Article

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