Test Directory

Test Code
5NUC
Test Name
5'Nucleotidase
CPT Codes
83915
Expected Turnaround Time
3 - 4 days
Clinical Utility

5′ nucleotidase is used to investigate the origin of increased serum alkaline phosphatase. It is a liver-related enzyme used to work up cholestatic/biliary obstruction. It parallels the increases of alkaline phosphatase and leucine aminopeptidase in hepatobiliary diseases, but is not usually elevated in skeletal disorders such as Paget disease of bone. It is increased with metastatic neoplasia in liver and in primary biliary cirrhosis, biliary obstruction from calculi and tumor.

Specimen and Container Info

Specimen Type:  Serum 

Alternate Specimen Type: Plasma


Collection Container: Gold Top, Serum Separator

Alternate Collection Container: Red Top Plain, Lavender Top (EDTA), Green Top (Sodium or Lithium Heparin)

 

Desired Specimen Volume: 1 mL 

Collection Instructions
  1. Collect a gold top, serum separator tube via venipuncture.
Processing and Submission Instructions
  1. Separate serum from cells.
  2. Transfer 1 mL of serum to a clear aliquot tube (screw cap).
Transport Instructions

Transport to the laboratory refrigerated.

Stability Requirements

Room Temperature

14 days

Refrigerated

14 days

Frozen

14 days

Freeze/Thaw Cycles

 Stable x3

Causes for Rejection
  • Hemolysis
Methodology
Kinetic
Reference Intervals

See patient report.

Reference Lab
Labcorp Of America Holdings
Testing Schedule
Routine, 3 times per week