Test Directory

Test Code
ACRBA
Test Name
Acetylcholine Receptor Autoantibody, Blocking
CPT Codes
86042
Expected Turnaround Time
3 - 7 days
Clinical Utility

Measurement of Acetylcholine Receptor (AChR)-blocking Antibodies in serum

Specimen and Container Info

Specimen Type: Serum

Collection Container: Gold Top, Serum Separator

Desired Specimen Volume: 1 mL

Collection Instructions
  1. Collect a gold top, serum separator tube via venipuncture.
Processing and Submission Instructions
  1. Separate serum from cells.
  2. Transfer 1 mL serum to a clear aliquot tube.
Patient Preparation

No isotopes administered 24 hours prior to venipuncture

Transport Instructions

Transport to the laboratory refrigerated. 

Stability Requirements

Room Temperature

13 days

Refrigerated

13 days

Frozen

13 days

Freeze/Thaw Cycles

 Stable x3

Methodology
Esoteric Immunoassay
Reference Intervals

 See patient report.

Limitations

In rare cases AChR antibodies can be found in patients with other autoimmune disorders or with thymoma without MG.

The causative autoantibody cannot be identified in up to 10 percent of patients with MG.

Alternate Names
  • AChR-blocking Antibodies
  • ACRAB
  • Anti-AChR Antibody
  • Myasthenia Gravis Antibody
Reference Lab
Labcorp Of America Holdings
Testing Schedule
Routine, 3 times per week