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Test Code
ACRAM
Test Name
AChR-modulating Ab
CPT Codes
86043
Expected Turnaround Time
5 - 7 days
Clinical Utility

Diagnose myasthenia gravis (MG); monitor response to treatment of myasthenia gravis
Specimen and Container Info

Specimen Type: Serum

Collection Container: Gold Top, Serum Separator

Alternate Collection Container: Red Top, Plain

Desired Specimen Volume: 0.5 mL
Collection Instructions
  1. Collect gold top, serum separator tube via venipuncture.
Processing and Submission Instructions
  1. Separate serum from cells.
  2. Transfer 0.5 mL of serum to a clear aliquot tube.
Transport Instructions

Transport to the laboratory refrigerated. 
Stability Requirements

Room Temperature

14 days

Refrigerated

14 days

Frozen

14 days

Freeze/Thaw Cycles

 Stable x3
Causes for Rejection
  • Improper labeling
  • Gross microbial contamination
  • Specimen contaminated with anticoagulants
  • Chylous serum
  • Plasma specimen
  • Excessive hemolysis
Methodology
Flow Cytometry
Reference Intervals

See patient report.
Limitations

In rare cases AChR antibodies can be found in patients with other autoimmune disorders or with thymoma without Myasthenia Gravis (MG).

The causative autoantibody cannot be identified in up to 10% of patients with MG.
Alternate Names
  •  Acetylcholine Receptor (AChR)-modulating Antibodies
Reference Lab
Labcorp Of America Holdings
Testing Schedule
Routine, 4 times per week
The American Medical Association (AMA) Current Procedural Terminology (CPT) codes published by HNL Lab Medicine are guidelines and are intended for informational purposes only. CPT coding is the exclusive responsibility of the billing entity. View the Terms.
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