Test Directory

Test Code
PTTP
Test Name
Activated Partial Thromboplastin Time Mixing Study
CPT Codes
85730
Included Tests
  • Activated Partial Thromboplastin Time

Reflexed when appropriate:

  • Thrombin Time
  • Reptilase Time
  • Activated Partial Thromboplastin Time Mixing Study
  • Activated Partial Thromboplastin Time Mixing Study, Incubated
Expected Turnaround Time
1 - 4 days
Clinical Utility

Distinguish specific (ie, factor VIII) and nonspecific (lupus anticoagulant) inhibitors; determine heparin presence; detect single or multiple factor deficiencies.

Specimen and Container Info

Specimen Type: Plasma  

Collection Container: 2 Full Light Blue Top (Sodium Citrate) 

Collection Instructions

Blood should be collected in a blue-top tube containing 3.2% buffered sodium citrate. Evacuated collection tubes must be filled to completion to ensure a proper blood-to-anticoagulant ratio.

Processing and Submission Instructions
Patient Preparation
Testing is contradictory for patients on anticoagulant therapy.
Transport Instructions
  • Inpatient: Transport to the laboratory at room temperature.
  • Outpatient: Transport to the laboratory frozen. 
Stability Requirements

Room Temperature

4 hours

Frozen

Platelet poor plasma: 14 days

Causes for Rejection
  • Clotted specimen
  • Specimen past stability
  • Specimen not properly filled
  • Specimen thawed in transit
Methodology
Mechanical Clot Detection
Reference Intervals

See Indvidual Test Listings.

Performing Location
Roble Road Core Laboratory
Alternate Names
  • PTT Mixing Study
  • APTT Mixing Study
Testing Schedule
Routine, Monday - Friday no holidays