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Test Code
ALSE
Test Name
Aldolase
CPT Codes
82085
Expected Turnaround Time
2 - 3 days
Clinical Utility

Evaluate muscle wasting process. High levels are found in progressive Duchenne muscular dystrophy (MD). Elevations occur in carriers of MD, in limb-girdle dystrophy and other dystrophies, in dermatomyositis, polymyositis, and trichinosis, but not in neurogenic atrophies (eg, multiple sclerosis or in myasthenia gravis).
Specimen and Container Info

Specimen Type: Serum

Alternate Specimen Type: Plasma

 

Collection Container: Gold Top, Serum Separator

Alternate Collection Container: Red Top, Plain, Lavender Top (EDTA), or Green Top (Sodium or Lithium Heparin)

 

Desired Specimen Volume: 0.5 mL
Collection Instructions
  1. Collect a gold top, serum separator tube via venipuncture.
Processing and Submission Instructions
  1. Separate serum from cells immediately after coagulation (30 minutes).
  2. Transfer 0.5 mL of serum to a clear aliquot tube (screw cap).
Transport Instructions

Transport to the laboratory refrigerated
Stability Requirements

Room Temperature

1 day

Refrigerated

7 days

Frozen

15 days

Freeze/Thaw Cycles

 Stable x3
Causes for Rejection
  • Hemolysis (red cells contain aldolase)
  • Gross lipemia
Methodology
Kinetic
Reference Intervals

See patient report.
Limitations

Not removing refrigerated specimens from the clot results in aldolase levels 12% to 46% higher.

As muscle mass diminishes, aldolase decreases. Serum aldolase elevation is not specific for muscle disease since it is present in many tissues
Reference Lab
Labcorp Of America Holdings
Testing Schedule
Monday-Friday
The American Medical Association (AMA) Current Procedural Terminology (CPT) codes published by HNL Lab Medicine are guidelines and are intended for informational purposes only. CPT coding is the exclusive responsibility of the billing entity. View the Terms.
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