Test Directory

Clear All
Test Code
RENR
Test Name
Aldosterone/Renin Activity Ratio
CPT Codes
82088, 84244
Included Tests
  • Aldosterone, LC/MS
  • Plasma Renin Activity, LC/MS/MS
Expected Turnaround Time
4-6 days
Clinical Utility

The Aldosterone-renin ratio is used to screen for primary aldosteronism.
Specimen and Container Info

Specimen Type: Plasma

Collection Container: Lavender Top (EDTA)

Desired Specimen Volume: 1.8 mL
Collection Instructions
  1. Collect a mid-morning blood sample after patient has been upright (sitting, standing, or walking) for a minimum of 2 hours, then have them sit 5-15 minutes prior to collection.
  2. Collect 2 lavender top (EDTA) tubes via venipuncture.
  3. Fill tubes to capacity with whole blood.
Processing and Submission Instructions
  1. Separate plasma from cells.
  2. Transfer at least 1.8 mL of plasma to a clear aliquot tube (screw cap).
Patient Preparation

Collect a mid-morning blood sample after patient has been upright (sitting, standing, or walking) for a minimum of 2 hours.
Transport Instructions

Transport to the laboratory frozen. 
Stability Requirements

Room Temperature

24 hours

Refrigerated

24 hours

Frozen

28 days
Causes for Rejection
  • Moderate to gross hemolysis
  • Plasma collected in a plasma separator tube (PPT)
  • Received thawed
Methodology
Chromatography/Mass Spectrometry
Reference Intervals

 See patient report.
Alternate Names
  • Plasma Renin Activity, LC-MS/MS
  • Aldosterone/Plasma Renin Activity Ratio, LC/MS/MS
  • ALDO/PRA Ratio
Reference Lab
Quest Diagnostics Nichols Institute
Testing Schedule
Routine, 6 times per week
The American Medical Association (AMA) Current Procedural Terminology (CPT) codes published by HNL Lab Medicine are guidelines and are intended for informational purposes only. CPT coding is the exclusive responsibility of the billing entity. View the Terms.
© 2026 HNL Lab Medicine. All rights reserved.