Test Directory

Test Code
A1AGY
Test Name
Alpha-1-Acid Glycoprotein
CPT Codes
83883
Expected Turnaround Time
4-6 days
Clinical Utility

This test is used to monitor acute-phase proteins associated with inflammatory conditions such as RA and malignant neoplasms.

Specimen and Container Info

Specimen Type: Serum 

Alternate Specimen Type: Plasma 

 

Collection Container: Gold Top, Serum Separator 

Alternate Collection Container:  Red Top, Plain or Green Top (Sodium or Lithium Heparin)

 

Desired Specimen Volume: 1 mL

Collection Instructions
  1. Collect a gold top serum separator tube via venipuncture.
Processing and Submission Instructions
  1. Separate serum from cells.
  2. Transfer 1 mL of serum to a clear aliquot tube (screw cap).
Transport Instructions

Transport to laboratory refrigerated

Stability Requirements

Room Temperature

14 days

Refrigerated

5 months

Frozen

1 year

Freeze/Thaw Cycles

Stable x1

Causes for Rejection
  • Gross lipemia that cannot be cleared by ultracentrifugation
  • Heat-inactivated samples
Methodology
Immunologic
Reference Intervals

See patient report.

Limitations

Patients with injuries, burns, or tumors exhibit elevated concentrations. Patients with chronic renal failure are found to have high concentrations of α1-acid glycoprotein, with no major difference reported between dialyzed and nondialyzed patients. Diminished concentrations due to restricted production of α1-acid glycoprotein are found in patients with chronic liver diseases. Low serum concentrations due to increased excretion of the protein are associated with nephritic syndrome.

Alternate Names
  • AAG
  • Alpha-1-Acid Glycoprotein
  • α1-Acid Glycoprotein
Reference Lab
Labcorp Of America Holdings
Testing Schedule
Varies