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Test Code
A1APN
Test Name
Alpha-1-Antitrypsin Phenotype
CPT Codes
82103, 82104
Included Tests
  • Alpha-1-Antitrypsin
  • Phenotype (PI)
Expected Turnaround Time
2 - 4 days
Clinical Utility

Definitive analysis of hereditary α1-antitrypsin deficiency, which is associated with chronic obstructive pulmonary disease (COPD) (panacinar emphysema), hepatic cirrhosis, and hepatoma. Cholestasis with neonatal hepatitis is found in a minority of neonates with α1AT deficiency.
Specimen and Container Info

Specimen Type: Serum 

 

Collection Container: Gold Top, Serum Separator 

Alternate Collection Container: Red Top, Plain 

 

Desired Specimen Volume: 2 mL 
Collection Instructions
  1. Collect a gold top, serum separator tube via venipuncture.
Processing and Submission Instructions
  1. Separate serum from cells.
  2. Transfer 2 mL of serum to a clear aliquot tube (screw cap)
Patient Preparation

 Overnight fasting is preferred.
Transport Instructions

Transport to laboratory refrigerated
Stability Requirements

Room Temperature

21 days

Refrigerated

21 days

Frozen

21 days

Freeze/Thaw Cycles

 Stable x2
Methodology
Varies By Test
Reference Intervals

 See patient report.
Limitations

α1-antitrypsin therapy may alter the patient phenotype.
Alternate Names
  • Alpha1-Antitrypsin Phenotyping
  • Pi Phenotype
  • Protease Inhibitors
Reference Lab
Labcorp Of America Holdings
Testing Schedule
Routine, Monday - Saturday
The American Medical Association (AMA) Current Procedural Terminology (CPT) codes published by HNL Lab Medicine are guidelines and are intended for informational purposes only. CPT coding is the exclusive responsibility of the billing entity. View the Terms.
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