Test Directory

Test Code
AFCSF
Test Name
Alpha Fetoprotein, CSF
CPT Codes
86316
Expected Turnaround Time
2 - 3 days
Clinical Utility

Elevated AFP levels have been seen not only in patients with non-seminomatous testicular cancer, but also in patients with other malignancies such as hepatocellular carcinoma, ovarian cancer, gastrointestinal cancer and pulmonary cancer. AFP is also frequently elevated in benign hepatic conditions such as acute viral hepatitis, chronic active hepatitis, and cirrhosis.

Specimen and Container Info

Specimen Type: Cerebrospinal Fluid

 

Collection Container: Sterile, Non-additive Container (CSF) 

Desired Specimen Volume: 3 mL

Collection Instructions
  1. Collect CSF specimen via lumbar puncture.
Processing and Submission Instructions
  1. Transfer 3 mL of CSF to a sterile aliquot tube (screw cap).
Transport Instructions

Transport to the laboratory frozen. 

Stability Requirements

Room Temperature

14 days

Refrigerated

28 days

Frozen

28 days

Causes for Rejection
  • Grossly lipemic
Methodology
Immunoassay
Reference Intervals

See patient report.

Reference Lab
Quest Diagnostics Nichols Institute
Testing Schedule
Routine, 5 times per week