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Test Code
AGALS
Test Name
Alpha-Galactosidase, Serum
CPT Codes
82657
Expected Turnaround Time
4 - 8 days
Clinical Utility

Diagnosis of Fabry disease in male patients.

Preferred screening test (serum) for Fabry disease.
Specimen and Container Info

Specimen Type: Serum

Preferred Collection Container: Gold Top, Serum Separator

Alternate Collection Container: Red Top, Plain

Desired Specimen Volume: 2 mL
Collection Instructions
  1. Collect a gold top, serum separator tube via venipuncture.
Processing and Submission Instructions
  1. Separate serum from cells.
  2. Transfer 2 mL of serum to a clear aliquot tube (screw cap).
Transport Instructions

Transport to the laboratory frozen. 
Stability Requirements

Refrigerated

24 hours

Frozen

14 days
Causes for Rejection

All specimens will be evaluated at Mayo Clinic Laboratories for test suitability
Methodology
Fluorometric
Reference Intervals

 See patient report.
Limitations

This test is not useful for patients undergoing a work up for a meat or meat-derived product allergy.

Individuals with pseudodeficiency allelic variants can show reduced alpha-galactosidase A enzyme activity with this assay.
Alternate Names
  • Alpha Galactosidase
  • Anderson Fabry Disease
  • Ceramide Trihexosidase
  • Fabry Disease
  • Fabry's Disease
  • Galactosidase, Alpha
  • GLA Deficiency
  • Anderson-Fabry Disease
Reference Lab
Mayo Clinic Laboratories
Testing Schedule
Routine, 2 times per week
The American Medical Association (AMA) Current Procedural Terminology (CPT) codes published by HNL Lab Medicine are guidelines and are intended for informational purposes only. CPT coding is the exclusive responsibility of the billing entity. View the Terms.
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