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Test Code
ADEVL
Test Name
Alzheimer Disease Evaluation, CSF
CPT Codes
82234, 84393, 84394
Included Tests
  • Abeta42, AD Interpretation
  • p-Tau/Abeta42
  • Phospho-Tau(181P)
  • Total-Tau
Expected Turnaround Time
1 - 4 days
Clinical Utility

Assessment of adults with cognitive impairment being evaluated for Alzheimer disease and other causes of cognitive impairment.


These assays should not be used to predict the development of dementia or other neurologic conditions or to monitor response to therapies.
Specimen and Container Info

Specimen Type: Cerebrospinal Fluid

 

Collection Container: Alzheimer's Disease Evaluation CSF Kit

Desired Specimen Volume: 2.5 mL
Collection Instructions
  1. Collect CSF specimen via lumbar puncture directly into collection kit tube.
Processing and Submission Instructions
  1. Transport 2.5 mL of CSF in the Alzheimer's Disease Evaluation Collection kit. Do not aliquot.
  2. Polystyrene collection tubes are NOT acceptable.
Transport Instructions

Transport to the laboratory refrigerated.

Stability Requirements

Room Temperature

12 hours

Refrigerated

14 days

Frozen

60 days
Causes for Rejection
  • Gross hemolysis
  • Gross icterus
Methodology
Electrochemiluminescence (Eclia)
Reference Intervals

See patient report.
Limitations

A positive cerebrospinal fluid (CSF) beta-amyloid 42 (Abeta42), total Tau (t-Tau), or phosphorylated Tau (p-Tau181) result, or p-Tau181/Abeta42 ratio does not establish a diagnosis of Alzheimer disease (AD) or other cognitive disorder. These results should be interpreted in combination with other clinical diagnostic and radiologic evaluations.
Reference Lab
Mayo Clinic Laboratories
Testing Schedule
Routine, 2 times per week
The American Medical Association (AMA) Current Procedural Terminology (CPT) codes published by HNL Lab Medicine are guidelines and are intended for informational purposes only. CPT coding is the exclusive responsibility of the billing entity. View the Terms.
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