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Test Code
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AMKP
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Test Name
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Amikacin, Peak
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CPT Codes
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80150
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Expected Turnaround Time
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Same day
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Clinical Utility
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Amikacin is effective in the treatment of serious gram-negative infections and is particularly useful in those strains resistant to other aminoglycosides. Monitoring serum/plasma concentrations of amikacin is useful because of the narrow margin between therapeutic effectiveness and toxicity.
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Specimen and Container Info
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Specimen | Container | Volume | Serum | Red Top, Plain | 1 mL | Serum | Gold Top, Serum Separator | 1 mL | Serum | Microtainer, Red Top | 500 µL | Serum | Microtainer, Serum Separator | 500 µL | Plasma | Lavendar Top (EDTA) | 1 mL | Plasma | Grey Top (Sodium Fluoride, Potassium Oxalate) | 1 mL | Plasma | Dark Green Top (Lithium Heparin) | 1 mL | Plasma | Microtainer, Lavender Top (EDTA) | 500 µL | Plasma | Microtainer, Green Gel | 500 µL |
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Collection Instructions
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Peak: Collect 30 minutes post infusion of IV dose.
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Processing and Submission Instructions
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- Centrifuge for 5 minutes at 3000 rpm and transfer serum or plasma to plastic aliquot tube.
- Freeze if delay in analysis will be more than 8 hours.
- Failure to freeze samples containing additional antibiotics may result in falsely low amikacin levels due to in vitro inactivation.
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Transport Instructions
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Transport serum or plasma aliquot to the laboratory frozen. |
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Stability Requirements
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Frozen
Store serum or plasma aliquots frozen. |
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Methodology
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Enzyme Immunoassay (EIA)
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Reference Intervals
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Age Group | Reference Interval | Units | All Ages | 20 - 35 | µg/mL |
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Performing Location
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Roble Road Core Laboratory
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Alternate Names
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Testing Schedule
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Routine daily, STAT testing available
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