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Test Code
AMANT
Test Name
Amitriptyline and Nortriptyline
CPT Codes
80299
Included Tests
  • Amitriptyline/Nortriptyline, Total
  • Amitriptyline
  • Nortiptyline
Expected Turnaround Time
2 - 5 days
Clinical Utility

Evaluate toxicity; monitor therapeutic levels.
Specimen and Container Info

Specimen Type: Serum

Alternate Specimen Type: Plasma

Collection Container: Red Top, Plain

Alternate Collection Container: Lavender Top (EDTA) or Green Top (Sodium or Lithium Heparin)

Desired Specimen Volume: 1 mL
Collection Instructions
  1. Collect a red top, plain tube via venipuncture.
  2. For therapeutic monitoring, collect specimen immediately prior to next dose unless specified otherwise.
Processing and Submission Instructions
  1. Separate serum from cells.
  2. Transfer 1 mL of serum to a clear aliquot tube (screw cap).
Transport Instructions

Transport to the laboratory refrigerated. 
Stability Requirements

Room Temperature

14 days

Refrigerated

14 days

Frozen

14 days

Freeze/Thaw Cycles

Stable x3
Causes for Rejection
  • Gel-barrier tube
Methodology
Liquid Chromatography - Tandem Mass Spectrometry (LC-MS/MS)
Reference Intervals

See patient report.
Limitations

The use of gel-barrier tubes is not recommended due to slow absorption of the drug by the gel. Depending on the specimen volume and storage time, the decrease in drug level due to absorption may be clinically significant.
Alternate Names
  • Elavil®
  • Endep®
Reference Lab
Labcorp Of America Holdings
Testing Schedule
Monday-Friday
The American Medical Association (AMA) Current Procedural Terminology (CPT) codes published by HNL Lab Medicine are guidelines and are intended for informational purposes only. CPT coding is the exclusive responsibility of the billing entity. View the Terms.
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