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Test Code
AMDA5
Test Name
AntiI-MDA-5 Antibody
CPT Codes
83516
Expected Turnaround Time
9 - 14 days
Clinical Utility
Anti-MDA5 antibodies are present in 7-35% of adult DM. Clinical features consist of absent or mild muscle symptoms (CADM), rapidly progressive ILD, specific mucocutaneous features of skin ulcerations and papules, oral ulcerations and arthritis.
Specimen and Container Info

Specimen Type: Serum

Preferred Collection Container: Red Top, Plain

Alternate Collection Container: Gold Top, Serum Separator

Desired Specimen Volume: 1 mL
Collection Instructions
  1. Collect a red top, plain tube via venipuncture.
Processing and Submission Instructions
  1. Separate serum from cells.
  2. Transfer 1 mL of serum to a clear aliquot tube (screw cap).
Transport Instructions

Transport to the laboratory refrigerated. 
Stability Requirements

Room Temperature

7 days

Refrigerated

14 days

Frozen

60 days
Causes for Rejection
  • Gross hemolysis
  • Gross lipemia
  • Gross icterus
  • Bacterial contamination.
Methodology
Enzyme Linked Immunosorbent Asasy (Elisa)
Reference Intervals

See patient report.
Alternate Names
  • Anti-melanoma differentiation-associated gene 5 clinically amyopathic dermatomyositis antibody
  • 140 kd (CADM-140)
Reference Lab
Mayo Clinic Laboratories
Testing Schedule
Routine, 6 times per week
The American Medical Association (AMA) Current Procedural Terminology (CPT) codes published by HNL Lab Medicine are guidelines and are intended for informational purposes only. CPT coding is the exclusive responsibility of the billing entity. View the Terms.
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