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Test Code
BCPCR
Test Name
B Cell Gene Rearrangement
Included Tests

Detection of clonal IgH gene rearrangements by PCR of IgH framework regions 1, 2, 3 and joining regions. In addition, Ig Kappa gene rearrangement analysis is performed using specific oligonucleotides recognizing the Vk, intragenic and Jk regions.
Expected Turnaround Time
7 - 10 business days
Clinical Utility
Detects monoclonal B cell immunoglobulin gene rearrangement. Interpret in clinical context for diagnosis of leukemia, lymphoma, and plasma cell dyscrasia.
Specimen and Container Info

Specimen

Container

Preferred Volume

Minimum Volume

Peripheral Blood

Lavender Top (EDTA)

5 mL

3 mL

Bone Marrow

Lavender Top (EDTA)

2 mL

1 mL

Fresh Tissue

RPMI

Two pieces, 0.2 cm³ each

One piece, 0.2 cm³

FFPE Tissue

Paraffin block

Paraffin Block

1 H&E slide plus 5-10 unstained slides cut at 5 or more microns from paraffin block
Collection Instructions

Please exclude biopsy needles, blades, and other foreign objects from collection containers.
Transport Instructions

Transport to the laboratory refrigerated.
Stability Requirements

Refrigerated

72 hours
Causes for Rejection
All specimens will be rejected if they are frozen.
Methodology
Molecular
Performing Location
Roble Road Core Laboratory
Alternate Names
  • B Cell Translocations
  • B Cell Clonality
Reference Lab
Neogenomics Laboratories, Inc.
Testing Schedule
Routine, Monday - Friday no holidays
The American Medical Association (AMA) Current Procedural Terminology (CPT) codes published by HNL Lab Medicine are guidelines and are intended for informational purposes only. CPT coding is the exclusive responsibility of the billing entity. View the Terms.
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