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Test Code
PPBNZ
Test Name
Benzodiazepines, Quantitative, Pain Management, Urine
CPT Codes
AMA 80346, CMS G0480
Expected Turnaround Time
1 - 5 days
Clinical Utility

Useful in determining the use or abuse of Benzodiazepines in urine compliance monitoring for pain management.

 

Testing includes identification and quantitation of:

  • Diazepam
  • Alpha-OH-Alprazolam
  • Lorazepam
  • Nordiazepam
  • Oxazepam
  • Temazepam
  • Alpha-OH-Midazolam
  • 7-Aminoclonazepam
Specimen and Container Info

Preferred Specimen Type: Urine

Preferred Collection Container: Plastic Urine Container (Preservative Free)

Desired Specimen Volume: 10 mL
Processing and Submission Instructions
  • If using paper requisition, submit specimen with a completed Pain Management Drug Testing Request (HNL-56).
  • Interpretation is dependent on completing the prescribed medication history section at the bottom of the form.
  • List only the medications taken within the last 2-3 days.
Transport Instructions

Transport to the laboratory refrigerated.
Stability Requirements

Refrigerated

 7 Days
Causes for Rejection

Urine specimens received in tubes containing preservatives will be rejected.
Methodology
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Reference Intervals

Interpretation and concentration of drug/metabolite in urine is dependent on dose, time of dose, metabolic rate, and hydration state.
Limitations

Analyte

Cutoff Concentration (ng/mL)

Diazepam

75

Alpha-OH-Alprazolam

75

Lorazepam

75

Nordiazepam

75

Oxazepam

75

Temazepam

75

Alpha-OH-Midazolam

75

7-Aminoclonazepam

75
Performing Location
Roble Road Core Laboratory
Alternate Names

 Alprazolam Alternate Names:

  • Alprazolam
  • Alphahydroxyalprazolam
  • Xanax
  • Alprax
  • Alzam
  • Tranax

 

Clonazepam Alternate Names:

  • Clonazepam
  • 7-aminoclonazepam
  • Klonopin
  • Rivitrol

 

Diazepam Alternate Names:

  • Valium
  • Diastat
  • Diazepam
  • Nordiazepam

 

Lorazepam Alternate Names:

  • Ativan
  • Loreev XR
  • Lorazepam

 

Oxazepam Alternate Names:

  • Serax
  • Oxazepam

 

Temazepam Alternate Names:

  • Restoril
  • Normison
  • Nortem
  • Temazepam

 

Midazolam Alternate Names:

  • Versed
  • Seizalam
  • Midazolam
  • Alphahydroxymidazolam
Testing Schedule
Routine, 5 times per week
The American Medical Association (AMA) Current Procedural Terminology (CPT) codes published by HNL Lab Medicine are guidelines and are intended for informational purposes only. CPT coding is the exclusive responsibility of the billing entity. View the Terms.
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