Test Directory

Test Code
AMYR
Test Name
Beta-Amyloid Ratio, CSF
CPT Codes
0358U
Included Tests
  • Beta-Amyloid Ratio
  • Beta-Amyloid Ratio Interpretation
Expected Turnaround Time
1 - 7 days
Clinical Utility

Assisting in the evaluation of adult patients, aged 55 years and older, presenting with cognitive impairment and are being assessed for Alzheimer disease and other causes of cognitive decline

This test is not intended as a screening or stand-alone diagnostic assay.

Specimen and Container Info

Specimen Type: Cerebrospinal Fluid

 

Collection Container: Alzheimer's Disease Evaluation CSF Kit (BlueTop SARSTEDT)

Desired Specimen Volume: 2.5 mL

Collection Instructions
  1. Collect CSF via lumbar puncture.
  2. Discard the first 1 to 2 mL of CSF.
  3. Discard any CSF visibly contaminated with blood.
  4. Collect CSF directly into the blue top Sarstedt tube included in the Alzheimer's Disease Evaluation Kit.

MCL Spinal Fluid Specimen Collection may be reviewed

Processing and Submission Instructions
  1. Transport 2.5 mL of CSF in the original collection tube provided with kit (BlueTop SARSTEDT).
Patient Preparation

This test is intended for use in adult patients aged 55 years and older. 

Transport Instructions

Transport to the laboratory refrigerated. 

Stability Requirements

Room Temperature

48 hours

Refrigerated

14 days

Frozen

90 days
Causes for Rejection
  • Gross hemolysis
  • Gross lipemia,
  • Gross icterus
  • Polystyrene collection tubes
Methodology
Chemiluminscent Immunoassay/Calculation
Reference Intervals

See patient report.

Limitations

Exposure of CSF to polystyrene tubes may result in falsely low beta-amyloid concentrations.

Alternate Names
  • Beta-Amyloid Ratio (1-42/1-40), Spinal Fluid
  • Amyloid Beta 42
  • Beta-Amyloid 42
  • Amyloid Beta 40
  • Beta-Amyloid 40
  • Amyloid ratio
  • Ab42/Ab40 ratio
Reference Lab
Mayo Clinic Laboratories
Testing Schedule
Routine, 1 time per week