Test Directory

Test Code
BUPM
Test Name
Bupropion and Metabolite
CPT Codes
80299
Included Tests
  • Bupropion
  • Hydroxybupropion
Expected Turnaround Time
Varies
Clinical Utility

Bupropion is an antidepressant for treating mental depression. Monitoring its level is important to optimize therapy, to avoid toxicity and to assure compliance.

Specimen and Container Info

Preferred Specimen Type: Serum

Alternate Specimen Type: Plasma

Preferred Collection Container: Red Top, Plain

Alternate Collection Container: Lavender Top (EDTA)

Desired Specimen Volume: 1 mL

Collection Instructions
  1. Collect a red top, plain tube via venipuncture.
Processing and Submission Instructions
  1. Separate serum from cells.
  2. Transfer 1 mL of serum to a clear aliquot tube (screw cap).
  3. Freeze immediately.
Patient Preparation

Collect as a trough prior to next dose.

Transport Instructions

Transport to the laboratory frozen. 

Stability Requirements

Frozen

30 days

Causes for Rejection
  • Room temperature or refrigerated specimen
  • Gel barrier/serum separator tube (SST)
Methodology
Chromatography/Mass Spectrometry
Reference Intervals

See patient report.

Reference Lab
Quest Diagnostics Nichols Institute
Testing Schedule
Routine, 3 times per week