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Test Code
ACRD
Test Name
Cardiolipin Autoantibody Profile
CPT Codes
86147 X 3
Included Tests
  • Cardiolipin IgA
  • Cardiolipin IgG
  • Cardiolipin IgM
Expected Turnaround Time
5 - 7 days
Clinical Utility

Elevated levels are seen either transiently in some infectious diseases or more persistently in autoimmune diseases, such as Systemic Lupus Erythematosus (SLE) and Antiphospholipid Syndrome (APS). Anticardiolipin antibodies have also been associated with fetal loss, endocarditis, cardiovascular disease, and hemolytic anemia. Testing is best utilized when performed in parallel with a Beta-2-Glycoprotein 1 Antibody Profile.
Specimen and Container Info

Preferred Specimen Type: Serum

Desired Specimen Volume: 2 mL

Preferred Collection Container: Gold Top, Serum Separator
Processing and Submission Instructions
  1. Allow specimen to sit upright for 30 minutes.
  2. Centrifuge 15 minutes.
Transport Instructions
Transport refrigerated.
Stability Requirements

Refrigerated

7 days

Frozen

<20°C for long-term storage

Freeze/Thaw Cycles

Avoid multiple freeze/thaw cycles.
Methodology
Semi-Quantitative Multiplex Bead Assay
Reference Intervals
  • Cardiolipin IgG: <20 GPL-U/mL, negative
  • Cardiolipin IgA: <20 APL-U/mL, negative
  • Cardiolipin IgM: <20 MPL-U/mL, negative
Performing Location
Roble Road Core Laboratory
Testing Schedule
Routine, Monday - Friday no holidays
The American Medical Association (AMA) Current Procedural Terminology (CPT) codes published by HNL Lab Medicine are guidelines and are intended for informational purposes only. CPT coding is the exclusive responsibility of the billing entity. View the Terms.
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