Test Directory

Test Code
CENAB
Test Name
Centromere Antibody, IgG
CPT Codes
83516
Expected Turnaround Time
4 - 7 days
Clinical Utility

Aids in diagnosis of systemic sclerosis (SSc). Negative results do not rule out SSc.

Specimen and Container Info

Preferred Specimen Type: Serum

Desired Specimen Volume: 2 mL

Preferred Collection Container: Gold Top, Serum Separator

Collection Instructions
Processing and Submission Instructions

Separator tubes: Contains clot activator and gel for separating serum from cells, but not anticoagulant. Separate serum from cells as soon as the clot has formed (30 minutes). If specimen is centrifuged before clotting is complete, a fibrin clot will form on top of the cell. This may cause the gel barrier to not be intact and could cause improper separation of serum and cells, possibly affecting test results.

Transport Instructions

Transport to the laboratory refrigerated. 

Stability Requirements

Refrigerated

Serum may be stored under refrigeration (2-8°C) for up to 7 days.

Frozen

<20°C for long-term storage. 

Freeze/Thaw Cycles

Avoid multiple freeze/thaw cycles. 

Causes for Rejection

Hemolyzed, or severely lipemic specimens.

Methodology
Semi-Quantitative Multiplex Bead Assay
Reference Intervals
SexAgeReference IntervalUnit
FemaleAll Age Groups<1.0AI
MaleAll Age Groups<1.0AI

<1.0 AI = Negative

Performing Location
Roble Road Core Laboratory
Testing Schedule
Routine, Monday - Friday no holidays