Test Directory

Test Code
SWCLA
Test Name
Chloride, Sweat
CPT Codes
89230
Included Tests
  • Sweat Chloride, Left Arm
  • Sweat Chloride, Right Arm
  • Interpretation
Expected Turnaround Time
1 day
Clinical Utility
Useful in confirming diagnosis of Cystic Fibrosis.

Specimen and Container Info

Preferred Specimen Type: Sweat

Desired Specimen Volume: 15µl sweat per sample submitted. Samples cannot be pooled. 

Alternate Specimen Volume: At minimum, the sample from one collection site must be 15µl or greater.

Preferred Collection Container: Sterile container.

Collection Instructions
Specimen containers must remain stoppered until analyzed. Handle with gloves only.
After obtaining specimen, transport immediately to the laboratory.
Processing and Submission Instructions

Testing must be scheduled through the Lehigh Valley Pediatric Pulmonology Office at the Lehigh Valley Children's Specialty Center. Patient information brochures explaining all details of testing are available through Lehigh Valley Hospital Network.

Stability Requirements

Room Temperature

72 hours

Refrigerated

72 hours
Methodology
Quantitative Chloride Determination By Coulometric Titration
Reference Intervals

Result

Interpretation

≤29 mmol/L

Results are inconsistent with the diagnosis of Cystic Fibrosis. Retesting is suggested if results do not correlate with clinical presentation.

30-59 mmol/L

Results are borderline and follow-up with repeat Sweat Chloride analysis and/or molecular diagnostic testing is suggested.

≥60 mmol/L

Results are consistent with the diagnosis of Cystic Fibrosis when accompanied by a positive clinical presentation.

 

Performing Location
Roble Road Core Laboratory
Testing Schedule
Routine, Monday through Friday. Testing must be scheduled through the Lehigh Valley Pediatric Pulmonology Office at the Lehigh Valley Childen's Specialty Center.