Test Directory

Test Code
CUINX
Test Name
Chronic Urticaria Index Test
CPT Codes
86343
Expected Turnaround Time
2 - 9 days
Clinical Utility

The CU Index test is the second generation Functional Anti-FceR test. Patients with a CU Index greater than or equal to 10 have basophil reactive factors in their serum which supports an autoimmune basis for disease.

Specimen and Container Info

Specimen Type: Serum

Preferred Collection Container: Gold Top, Serum Separator

Alternate Collection Container: Red Top, Plain

Desired Specimen Volume: 2 mL

Collection Instructions
  1. Collect a gold top, serum separator tube via venipuncture.
Processing and Submission Instructions
  1. Separate serum from cells within two hours of collection.
  2. Transfer 2 mL of serum to a clear aliquot tube (screw cap).
Patient Preparation
Patients taking calcineurin inhibitors should stop medication 72 hours prior to draw. Patients taking prednisone should be off their medication for 2 weeks prior to draw.
Transport Instructions

Transport to the laboratory refrigerated. 

Stability Requirements

Room Temperature

14 days

Refrigerated

14 days

Frozen

14 days
Methodology
Ex-Vivo Challenge, Cell Culture, And Histamine Analysis
Reference Intervals

See patient portal.

Limitations

A positive result does not indicate which autoantibody (anti-IgE, anti-FceRI or anti-FCERII) is present.

Alternate Names
  • FCUIX
Reference Lab
Mayo Clinic Laboratories
Testing Schedule
Routine, 2 times per week