Test Directory

Test Code
CITLP
Test Name
Citalopram, Quantitative, Whole Blood
CPT Codes
AMA 80332, CMS G0480
Expected Turnaround Time
5 - 7 days
Clinical Utility
  • Citalopram (Celexa) and Escitalopram (Lexapro) are approved for the treatment of depression. Although routine therapeutic drug monitoring is not indicated, this test is useful for identifying compliance and/or overdose.
  • This test includes identification and quantitation of:

Citalopram

Specimen and Container Info

Specimen

Container

Volume

Whole Blood

Grey Top* (Sodium Fluoride, Potassium Oxalate)

3 mL

Whole Blood

Dark Green Top (Lithium Heparin)

3 mL

Whole Blood

Lavender Top (EDTA)

3 mL

Serum

Red Top, Plain

1 mL

*Preferred Specimen 

Processing and Submission Instructions

For forensic or legal purposes, submit specimen in a plastic evidence bag with a Chain-of-Custody Form.

Transport Instructions

Transport to the laboratory refrigerated.

Stability Requirements

Room Temperature

 7 days

Refrigerated

 7 days

Causes for Rejection

Specimens collected in separator tubes will be rejected. 

Methodology
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Reference Intervals

 Analyte

Therapeutic Range (ng/mL)

Toxic (ng/mL)

R,S Citalopram

100-250

>300

S Citalopram

50-130

>300

**Note: This method is not chiral specific.

Limitations

Analyte

Reporting Limit (ng/mL)

Citalopram

25

Performing Location
Roble Road Core Laboratory
Alternate Names
  • Celexa
  • Lexapro
Testing Schedule
Routine, 2 times per week