Test Directory

Coenzyme Q10 (CoQ10) is also referred to as ubiquinone because it can be found in almost all eukaryotic cells. CoQ10 embedded in the inner mitochondrial membrane is an essential component of the electron transport chain and plays a role in the ATP-producing oxidative phosphorylation. CoQ10 is also a powerful lipid-soluble antioxidant protecting cell membranes and lipoproteins. CoQ10 is present in the plasma in both the reduced (ubiquinol) and oxidized (ubiquinone) forms. The reduced form of CoQ10 is the only endogenously synthesized lipophilic antioxidant and as such, serves to protect biological membranes against oxidation as well as inhibiting the peroxidation of lipoproteins in the circulation. Reduced CoQ10 in plasma may also have a role recycling vitamin E (alpha-tocopherol).

Specimen Type: Serum

Collection Container: Gold Top, Serum Separator

Alternate Collection Container: Red Top, Plain

Desired Specimen Volume: 0.5 mL

1. Collect a gold top, serum separator tube via venipuncture

1. Separate serum from cells.
2. Transfer 0.5 mL of serum to an amber aliquot tube.
3. If an amber aliquot tube is not available, cover entire tube and cap in aluminum foil.

Transport to the laboratory protected from light and refrigerated.

• Serum unprotected from light

See patient report.

• CoQ10
• Ubiquinone 50
• Coenzyme Q10, Total