Test Directory

• Creatinine(Crt),U
• Copper,Urine 24 Hr
• Copper, Urine
• Copper/Crt Ratio

Monitor exposure to copper.

Specimen Type: 24 Hour Urine

Alternate Specimen Type: Random Urine

Collection Container: 24 Hour Plastic Urine Container

Alternate Collection Container: Plastic Urine Container (Preservative Free) 

Desired Specimen Volume: 5 mL

1. Obtain a 24-hour or random urine collection.

For 24 hour collections:

1. Instruct the patient to void at 8 AM and discard the specimen.
2. Then collect all urine including the final specimen voided at the end of the 24-hour collection period (ie, 8 AM the next morning)
3. Specimen must be collected in a plastic container and refrigerated during collection.
4. Screw the lid on securely.

1. Transfer 5mL of urine to a certified metal-free aliquot tube(s).
2. Record total volume and collection time interval on the aliquot tube and on test request form if applicable.

Transport to the laboratory refrigerated. 

 See patient report.

Increased urinary copper excretion may occur in ICC or with chronic active hepatitis; Wilson's disease and chronic active hepatitis may also resemble one another; thus, parameters in addition to urinary copper excretion, such as ceruloplasmin and serum copper, are needed.

•  Cu, Urine