Test Directory

Test Code
CRYOB
Test Name
Cryoglobulin, Qualitative
CPT Codes
82595
Expected Turnaround Time
4 - 8 days
Clinical Utility

Cryoglobulins may be present in macroglobulinemia of Waldenström, myeloma, chronic lymphocytic leukemia, lupus, chronic active hepatitis, and other viral infections.

Specimen and Container Info

Specimen Type: Serum

Collection Container: Red Top, Plain

Specimen Volume: 3 mL

Collection Instructions
  1. Collect a prewarmed red top, plain tube via venipuncture
Processing and Submission Instructions
  1. Separate serum from cells immediately after clot formation (keep at 37°C while clotting)
  2. Transfer 3 mL of serum to a clear aliquot tube (screw cap).
  3. Label aliquot tube as "prewarmed".
Patient Preparation

Patient must be fasting. Testing will be cancelled by reference lab if patient is not fasting.

Transport Instructions

Transport to the laboratory at room temperature.  

Stability Requirements

Room Temperature

72 hours

Causes for Rejection
  • Specimen not allowed to clot at 37°C
  • Patient not fasting
  • Lipemia
  • Gel-barrier tube used for collection
  • Whole blood received
Methodology
Visual Observation of Refrigerated Samples
Reference Intervals

See patient report.

Reference Lab
Labcorp Of America Holdings
Testing Schedule
Routine, Monday - Saturday
Reflex Tests
IFEEC
What triggers the reflex testing
reflex quantitation (as percentage) and immunofixation of cryoprecipitate if positive