Test Directory

Test Code
CRYPS
Test Name
Cryptococcal Antigen, Serum
CPT Codes
86403
Included Tests
  • Antigen Detection
  • Reflex to titer if positive
Expected Turnaround Time
1 - 3 days
Clinical Utility

Cryptococcosis is a systemic infection caused by Cryptococcus neoformans. The organism initially causes a pulmonary infection which is often subclinical, but rapidly disseminates and shows a predilection for the central nervous system. Positive screens will be reflexed to titer.

Specimen and Container Info

Specimen: Serum

Collection Container: Red Top, No Serum Separator

Desired Volume: 0.5 mL

Minimum Acceptable Volume: 0.25 mL

Processing and Submission Instructions
  1. Allow tube to clot upright for at least 60 minutes.
  2. Separate serum from cells within 2 hours of collection
  3. Transfer 0.5 mL of serum to a plastic aliquot tube.
Transport Instructions

 Transport to the laboratory refrigerated.

Stability Requirements

Room Temperature

24 hours

Refrigerated

72 hours

Methodology
Latex Agglutination
Performing Location
Roble Road Core Laboratory
Testing Schedule
Routine, Monday-Friday - no holidays