Test Directory

Test Code
CMVR5
Test Name
Cytomegalovirus Drug Resistance, 5 Drug
CPT Codes
87900, 87910
Included Tests
  • Ganciclovir,GCV
  • Foscarnet,FOS
  • Cidofovir,CDV
  • Letermovir,LTV
Expected Turnaround Time
3 - 9 days
Clinical Utility

Provides antiviral susceptibility information for ganciclovir, foscarnet, cidofovir, maribavir, and letermovir.

Specimen and Container Info

Specimen Type: Plasma

Collection Container: Lavender Top (EDTA)

Alternate Collection Container: White Top (EDTA) or Pink Top (EDTA)

Desired Specimen Volume: 3 mL

Collection Instructions
  1. Collect a lavender top (EDTA) tube via venipuncture
Processing and Submission Instructions
  1. Separate plasma from cells within 24 hours of collection.
  2. Transfer 3 mL of plasma to a clear aliquot tube (screw cap).
  3. If available, please include the following on the packing list: most recent viral load and test date; information on current or past drug therapy.
Patient Preparation

This test is intended for patients with a viral load >2.6 log IU/mL.

Transport Instructions

Transport to the laboratory frozen. 

Stability Requirements

Room Temperature

8 hours

Refrigerated

72 hours

Frozen

1 month
Causes for Rejection
  • Serum
  • Heparinized specimens
Methodology
Massively Parallel Sequencing
Reference Intervals

See patient report.

Limitations

This test may be unsuccessful if the plasma CMV DNA viral load is less than 2.6 log IU/mL.

Alternate Names
  • Cytomegalovirus (CMV) drug resistance, next generation sequencing
  • Cytomegalovirus (CMV) genotype
  • Cytomegalovirus antiviral drug resistance
Reference Lab
ARUP Laboratories
Testing Schedule
Routine, daily