Test Directory

Test Code
DRVVT
Test Name
Dilute Russell's Viper Venom Time (DRVVT)
CPT Codes
85613
Included Tests
  • DRVVT Screen

Reflexed when appropriate:

  • DRVVT Confirm
Expected Turnaround Time
4 - 7 days
Clinical Utility

Qualitative detection of lupus anticoagulants in plasma. A normal or negative dRVVT screen shows no evidence of LUA in the dRVVT assay. A negative result does not necessarily rule out the presence of an LUA or an APL antibody. Due to the heterogeneity associated with lupus anticoagulants, performance of two or more different screening assays may significantly enhance LUA detection. A positive dRVVT screen with positive reflex confirmation indicates that the presence of LUA is suggested by the dRVVT. Results should be interpreted in light of clinical history and in conjunction with other laboratory findings.

Specimen and Container Info

Specimen Type: Plasma

Collection Container: 2 Full Light Blue Top (Sodium Citrate)  

Collection Instructions

Blood should be collected in a blue-top tube containing 3.2% buffered sodium citrate. Evacuated collection tubes must be filled to completion to ensure a proper blood-to-anticoagulant ratio.

Processing and Submission Instructions
Patient Preparation
Testing is contradictory for patients on anticoagulant therapy.
Transport Instructions

Transport to the laboratory frozen. 

Stability Requirements

Frozen

Platelet poor plasma: 14 days

Causes for Rejection
  • Gross hemolysis
  • Platelet poor plasma thawed in transit
  • Specimens past stability
Methodology
Mechanical Clot Detection
Reference Intervals
  • DRVVT screen: 27.7 - 43.6 seconds
  • DRVVT confirmation: <1.4
Performing Location
Roble Road Core Laboratory
Testing Schedule
Monday-Friday