Test Directory

Test Code
DULX
Test Name
Duloxetine, Quantitative, Whole Blood
CPT Codes
AMA 80332, CMS G0480
Expected Turnaround Time
5 - 7 days
Clinical Utility

Duloxetine is used to treat symptoms of depression, neuropathic pain, fibromyalgia, and urinary stress incontinence. Routine drug monitoring is not indicated but may be useful for identifying patient compliance and/or toxicity. Useful in determining the use or abuse of Duloxetine.

Testing includes identification and quantitation of:

  • Duloxetine
Specimen and Container Info

Specimen

Container

Volume

Whole Blood

Grey Top* (Sodium Fluoride, Potassium Oxalate)

3 mL

Whole Blood

Dark Green Top (Lithium Heparin)

3 mL

Whole Blood

Lavender Top (EDTA)

3 mL

Serum

Red Top, Plain

1 mL

*Preferred Specimen

Processing and Submission Instructions

For forensic or legal purposes, submit specimen in a plastic evidence bag with a Chain-of-Custody Form.

Transport Instructions

Transport to the laboratory refrigerated.

Stability Requirements

Room Temperature

 7 days

Refrigerated

 7 days

Causes for Rejection

Specimens collected in separator tubes will be rejected.

Methodology
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Reference Intervals

 Analyte

Therapeutic Range (ng/mL)

Duloxetine

60-120

Limitations

Analyte

Reporting Limit (ng/mL)

Duloxetine

25

Performing Location
Roble Road Core Laboratory
Alternate Names
  • Cymbalta
  • Yentreve
Testing Schedule
Routine, 2 times per week