Test Directory

Clear All
Test Code
UES3
Test Name
Estriol, Unconjugated
CPT Codes
82677
Expected Turnaround Time
4-6 days
Clinical Utility

The placenta converts DHEA-S, produced by the fetal adrenals, to Estriol and other estrogens. Estriol is useful in assessing the fetal adrenals and placenta during pregnancy. More commonly, Estriol is one of the maternal serum biochemical markers used to screen for common chromosomal trisomies, especially Down syndrome.
Specimen and Container Info

Specimen Type: Serum 

  

Collection Container: Red Top, Plain

Desired Specimen Volume: 0.5 mL
Collection Instructions
  1. Collect a red top, plain tube via venipuncture.
Processing and Submission Instructions
  1. Separate serum from cells.
  2. Transfer 0.5 mL of serum to a clear aliquot tube (screw cap).
Transport Instructions

Transport to the laboratory refrigerated. 
Stability Requirements

Room Temperature

5 days

Refrigerated

7 days

Frozen

28 days
Causes for Rejection
  • Serum separator tube (SST)
Methodology
Chromatography/Mass Spectrometry
Reference Intervals

See patient report.
Alternate Names
  • Estriol, Serum
Reference Lab
Quest Diagnostics Nichols Institute
Testing Schedule
Routine, 6 times per week
The American Medical Association (AMA) Current Procedural Terminology (CPT) codes published by HNL Lab Medicine are guidelines and are intended for informational purposes only. CPT coding is the exclusive responsibility of the billing entity. View the Terms.
© 2026 HNL Lab Medicine. All rights reserved.