Test Directory

Test Code
XIII
Test Name
Factor XIII Screen
CPT Codes
85291
Expected Turnaround Time
5 - 7 days
Clinical Utility

Factor Thirteen (FXIII) stabilizes fibrin clots; hence, FXIII deficiency can cause delayed post-traumatic bleeding and delayed wound healing. Spontaneous abortions and sterility (in men) are seen in homozygous inheritance.

Specimen and Container Info

Preferred Specimen Type: Plasma

Desired Specimen Volume:

  • Adults: 1.0 mL plasma split into 2 tubes from one appropriately filled Light Blue Top (Sodium Citrate) tube.
  • Neonates: 0.5 mL of plasma aliquoted into 1 tube from one appropriately filled pediatric Light Blue Top (Sodium Citrate) tube.

Preferred Collection Container: Light Blue Top (Sodium Citrate)

Processing and Submission Instructions
  1. Immediately after draw, centrifuge blue top tubes at 3000 rpm for 10 minutes.
  2. Aliquot citrated plasma evenly into 2 aliquot tubes, with no more than 1.5 mL plasma placed in each tube.
  3. Be careful not to disturb cells when drawing off the plasma.
  4. Identify specimen with patient and “Citrated Plasma” labels.
  5. Tubes should be securely capped, labeled, and frozen at -70° C.
  6. Specimens should remain frozen until time of testing.
Transport Instructions

Transport aliquoted plasma submerged in dry ice.

Stability Requirements

Frozen

30 days at -70° C
Methodology
Manual Clot Evaluation
Reference Intervals

Adequate; no clot dissolution in 24 hours.

Performing Location
Roble Road Core Laboratory
Testing Schedule
Routine, 1 time per week