Test Directory

• Free Kappa Lt Chains,Ur
• Free Lambda Lt Chains,Ur
• Kappa/Lambda Ratio,U

The urine free light chain (FLC) assay can be used to monitor disease progression or response to therapy in patients where urine protein electrophoresis (PE) is unable to provide reliable Bence Jones Protein quantification.

Specimen Type: 24 Hour Urine

Alternate Specimen Type: Random Urine

Collection Container: 24 Hour Plastic Urine Container

Alternate Collection Container: Plastic Urine Container (Preservative Free) 

Desired Specimen Volume: 1.5 mL

1. Collect random urine in a sterile container or collect 24-hour urine in timed urine collection jug.

1. Transfer 1.5 mL of urine to a clear aliquot tube (screw cap).

Transport to the laboratory refrigerated. 

• Microbially-contaminated specimen
• Specimen containing particulate matter

See patient report.

Urine FLC quantitation may be misleading in specimens with high levels of urinary polyclonal free light chains with absent Bence Jones protein by urine immunofixation. Therefore, correlation with urine immunofixation (ur IFE) is needed to identify inconsistent results.

Values obtained with different assay methods should not be used interchangeably in serial testing. It is recommended that only one assay method be used consistently to monitor each patient's course of therapy. This procedure does not provide serial monitoring; it is intended for one-time use only.

• Free Light Chains, Quantitative, Urine
• Kappa Free Light Chains, Quantitative, Urine
• Kappa:Lambda Free Light Chains Ratio, Quantitative, Urine
• Kappa:Lambda Free Light Chains, Quantitative, Urine
• Lambda Free Light Chains, Quantitative, Urine
• Light Chains, Free κ and λ, Quantitative, Urine