Test Directory

Test Code
GBMAB
Test Name
GBM Autoantibody
CPT Codes
83516
Clinical Utility

Anti-GBM antibodies (glomerular basal membrane; Goodpasture Antigen) are important for the diagnosis of glomerulonephritis, which may be accompanied by pulmonary hemorrhage (Goodpasture pulmo-renal Syndrome). Due to clinical symptoms similar with systemic vasculitis, it is appropriate to concurrently carry out tests for anti-GBM and antineutrophil cytoplasmic antibodies (ANCA).

Specimen and Container Info

Specimen Type: Serum

Desired Specimen Volume: 2 mL

Collection Container: Gold Top, Serum Separator

Processing and Submission Instructions

Separator tubes: Contains clot activator and gel for separating serum from cells, but not anticoagulant. Separate serum from cells as soon as the clot has formed (30 minutes). If specimen is centrifuged before clotting is complete, a fibrin clot will form on top of the cell. This may cause the gel barrier to not be intact and could cause improper separation of serum and cells, possibly affecting test results.

Transport Instructions

Transport refrigerated

Stability Requirements

Refrigerated

7 days

Frozen

For longer storage of samples, keep at -20°C or colder.

Methodology
Semi-Quantitative Multiplex Bead Assay
Reference Intervals
SexAgeReference IntervalUnit
FemaleAll Age Groups<1.0AI
MaleAll Age Groups<1.0AI
Performing Location
Roble Road Core Laboratory
Testing Schedule
Routine, Monday - Friday no holidays