Test Directory

Test Code
BSBP
Test Name
Group B Streptococcus, PCR
CPT Codes
87653
Included Tests
  • Group B Streptococcus, PCR
  • Culture and sensitivity will be performed in patients with a noted penicillin allergy
Expected Turnaround Time
1 - 2 day
Clinical Utility

Group B Streptococcus (GBS) causes invasive disease in infants and can be spread vertically from colonized women during delivery. Standard of care is for the screening of pregnant women at 35 - 37 weeks of gestation to determine colonization status.

Specimen and Container Info

Specimen: Vaginal/Rectal Swab

Collection Container: Eswab

Collection Instructions
  1. Patient should be collected at 36 - 37 weeks of gestation.
  2. Wipe away excessive amount of secretion or discharge from the vaginal area.
  3. Carefully insert swab into the lower one-third of the vagina and sample secretions from the mucosa. Do not collect a cervical specimen.
  4. Carefully insert the same swab, approximately 2.5 cm beyond the anal sphincter, and gently rotate to sample anal crypts.
  5. Place the swab in the collection container.
Processing and Submission Instructions
  • Please indicate patient's penicillin allergy status.
  • Reflex culture and susceptibility will be performed on positive specimens for penicillin allergic individuals.
Transport Instructions

Transport to the laboratory at room temperature.

Stability Requirements

Room Temperature

24 hours

Refrigerated

6 days
Causes for Rejection

Specimen other than vaginal/rectal swabs are unacceptable.

Methodology
Real Time Polymerase Chain Reaction (PCR)
Limitations

Collection of both sites is highly encouraged by CDC recommendations. Failure to collect from both sites significantly decreases detection of GBS.

Performing Location
Roble Road Core Laboratory
Alternate Names
  • GBS PCR
  • Group B Strep PCR
  • Streptococcus agalactiae Molecular Detection
Testing Schedule
Routine, daily