Test Directory

Test Code
HPBRT
Test Name
Helicobacter pylori Breath Test
CPT Codes
83013
Included Tests

Analysis of pre- and postbreath samples to detect 13CO2

Expected Turnaround Time
1 - 4 days
Clinical Utility

The urea breath test can be used to aid in the diagnosis of H pylori infection. The test can also be used to assess therapy when it is administered more than a month after completion of therapy.

Specimen and Container Info

Specimen Type: Breath Sample Bags

Collection Container: One blue sample bag labelled "baseline" AND one "postdose" sample bag

Desired Volume: One pre- and one post-ingestion breath sample

Collection Instructions

Blue sample bag (baseline) must be collected as follows:

  1. Remove the blue breath collection bag from the kit and remove the pulloff cap from mouthpiece of the breath collection bag. 
  2. Instruct the patient to breathe normally, then take a deep breath, pause holding their breath for a full second (counting one, one thousand) then exhale into the mouthpiece of the bag. Replace the cap in the mouth piece of the bag.
  3. Prepare the fruit-flavored powder solution, containing 13C-urea diagnostic component as detailed in the kit instructions 

Postdose sample bag is collected as follows:

  1.  Instruct the patient to drink all the solution without “rinsing” mouth before swallowing
  2.  Have the patient sit quietly for 15 minutes. 
  3. After 15 minutes, collect the gray sample bag as outlined for the baseline specimen above
Processing and Submission Instructions

Call Referral Testing for test kit availability.

Patient Preparation
  • The patient should fast for at least one hour prior to testing.
  • The patient should not take antimicrobials, proton pump inhibitors, or bismuth preparations within two weeks prior to testing.
  • Note: Solution contains phenylalanine. Phenylketonurics should be warned.
Transport Instructions

Transport to the laboratory at room temperature.  

Stability Requirements

Room Temperature

7 days

Causes for Rejection
  • Specimens collected from persons younger than 3 years of age
Methodology
IR (infrared) spectroscopy to assess the presence of 13CO2
Reference Intervals

See patient report.

Alternate Names
  • Ubit
  • Urea Breath Test
Reference Lab
Labcorp Of America Holdings
Testing Schedule
Routine, Monday - Saturday