Test Directory

Test Code
HIPRF
Test Name
Heparin-induced Platelet Antibody With Serotonin Release Assay Reflex
CPT Codes
86022
Expected Turnaround Time
1 - 4 days
Clinical Utility

This test is used to assist in the diagnosis of heparin-induced thrombocytopenia.

Specimen and Container Info

Specimen Type: Serum

Collection Container: Gold Top, Serum Separator

Alternate Collection Container: Red Top, Plain

Desired Specimen Volume: 2 mL

Collection Instructions
  1. Collect a gold top, serum separator tube via venipuncture.
Processing and Submission Instructions
  1. Separate serum from cells.
  2. Transfer 2 mL of serum to a LabCorp pp transpak frozen purple tube and freeze immediately.
  3. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.
Transport Instructions

Transport to the laboratory frozen. 

Stability Requirements

Frozen

15 days

Causes for Rejection
  • Hemolyzed
  • Lipemic
  • Icteric
  • Microbially contaminated
  • Heat-inactivated samples
Methodology
Varies By Test
Reference Intervals

See patient report.

Limitations

HIPA results should not be the sole basis for establishing the diagnosis of heparin-induced thrombocytopenia. Some patients with HIPA will not develop symptoms of heparin-induced thrombocytopenia (HIT). Microbial contamination, lipemia, icterus, or hemolysis may interfere with this test and immune complexes or immunoglobulin aggregates in the patient sample can produce false-positive results. Heparin in the sample (>1 unit/mL) can produce false-negative results.

Alternate Names
  • Vaccine-Associated Coagulopathy
  • Vaccine-Induced Immune Thrombotic Thrombocytopenia
  • VITT Antibody Test
Reference Lab
Labcorp Of America Holdings
Testing Schedule
Varies
Reflex Tests
SRASY
What triggers the reflex testing
Heparin-induced Platelet Antibody will reflex to Serotonin Release Assay when HIPA value is greater than 0.400 OD units.