Test Directory

Clear All
Test Code
HBVGS
Test Name
Hepatitis B Genotype by Sequencing
CPT Codes
87912
Included Tests
  • HBV Genotype
  • Polymerase mutations
  • Precore Mutation
  • BCP Mutations
Expected Turnaround Time
8 - 12 days
Clinical Utility

This test is used to identify HBV genotype (A-H) for epidemiology or prognostic purposes and to detect hepatitis B virus (HBV) mutations associated with resistance to antiviral agents.
Specimen and Container Info

Preferred Specimen Type: Plasma

Alternate Specimen Type: Serum

Preferred Collection Container: White Top (EDTA)

Alternate Collection Container: Lavender Top (EDTA) or Gold Top, Serum Separator

Desired Specimen Volume: 1 mL
Collection Instructions
  1. Collect a white top (EDTA) tube via venipuncture
Processing and Submission Instructions
  1. Separate plasma from cells within two hours of collection.
  2. Transfer 1 mL of plasma to a clear aliquot tube (screw cap).
Transport Instructions

Transport to the laboratory frozen. 
Stability Requirements

Room Temperature

72 hours

Refrigerated

7 days

Frozen

30 days
Causes for Rejection
  • Unspun PPT tube
Methodology
Polymerase Chain Reaction (PCR) | Sequencing
Reference Intervals

See patient report.
Limitations

This test can only be performed reliably on specimens with a viral load of at least 600 IU/mL.

Alternate Names
  • Hepatitis B Virus Drug Resistance, Genotype, and BCP/Precore Mutations
Reference Lab
Quest Diagnostics Nichols Institute
Testing Schedule
Routine, 2 times per week
The American Medical Association (AMA) Current Procedural Terminology (CPT) codes published by HNL Lab Medicine are guidelines and are intended for informational purposes only. CPT coding is the exclusive responsibility of the billing entity. View the Terms.
© 2026 HNL Lab Medicine. All rights reserved.