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Test Code
GSHCV
Test Name
Hepatitis C Virus, GenoSure
CPT Codes
87900, 87902
Expected Turnaround Time
10 - 14 days
Clinical Utility
Assessment of drug susceptibility by nucleic acid sequencing of a patient's hepatitis C virus (HCV) to the NS3/4A protease inhibitors. Detects Q80K polymorphism. Assay should be used for patients with documented HCV genotype 1.
Specimen and Container Info

Preferred Specimen Type: Plasma

Alternate Specimen Type: Serum

Preferred Collection Container: White Top (Plasma Preparation Tube); OR Lavender Top (EDTA)

Alternate Collection Container: Gold Top, Serum Separator

Desired Specimen Volume: 2 mL
Collection Instructions
  1. Collect specimen in a white top (PPT) tube; lavender top (EDTA) tube; OR gold top, serum separator tube via venipuncture.
  2. Centrifuge specimen within six hours of collection, remove serum or plasma, and transfer to polypropylene screw-capped tube or clear aliquot tube.
Processing and Submission Instructions

Please indicate the patient's HCV genotype (1a or 1b)
Transport Instructions

Transport to the laboratory frozen. 
Stability Requirements

Room Temperature

6 hours

Refrigerated

 24 hours

Frozen

2 weeks at -20°F

6 weeks at -70°F
Causes for Rejection
  • Not centrifuged
  • Insufficient volume
  • Heparanized plasma
  • Nonfrozen specimens
  • Specimens exposed to repeated freeze/thaw cycles
  • Specimen received in "pop-top" or "snap cap" tube.
Methodology
Polymerase Chain Reaction (Pcr) Amplification And Dna Next Generation Sequencing
Reference Intervals

 See patient report.
Limitations

This procedure may not be successful when the viral load is <2000 IU/mL. This assay requires an HCV genotype of either 1a or 1b.
Reference Lab
Labcorp Of America Holdings
Testing Schedule
Varies
The American Medical Association (AMA) Current Procedural Terminology (CPT) codes published by HNL Lab Medicine are guidelines and are intended for informational purposes only. CPT coding is the exclusive responsibility of the billing entity. View the Terms.
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