Test Directory

Test Code
HPPL
Test Name
Hexagonal Phase Phospholipid
CPT Codes
85598
Expected Turnaround Time
4 - 7 days
Clinical Utility

Lupus anticoagulant antibodies are heterogeneous; if DRVVT is negative, lupus anticoagulant hexagonal phase will increase the possibility of detecting the inhibitor. A normal or negative Staclot LA (TM) and shows no evidence of LUA in this type of assay. A negative result does not necessarily rule out the presence of an LUA or an APL antibody. Due to the heterogeneity associated with lupus anticoagulants, performance of two or more different LUA assays may significantly enhance LUA detection and interpretation. A positive (>8.0) Staclot LA (TM) and indicates that the presence of LUA is suggested. Results should be interpreted in light of clinical history and in conjunction with other laboratory findings.

Specimen and Container Info

Specimen Type: Plasma

Collection Container: 1 Full Light Blue Top (Sodium Citrate) 

Collection Instructions

Blood should be collected in a blue-top tube containing 3.2% buffered sodium citrate. Evacuated collection tubes must be filled to completion to ensure a proper blood-to-anticoagulant ratio.

Processing and Submission Instructions
Patient Preparation
Testing is contradictory for patients on anticoagulant therapy.
Transport Instructions

Transport to the laboratory frozen. 

Stability Requirements

Frozen

Platelet poor plasma: 14 days

Causes for Rejection
  • Platelet poor plasma thawed in transit
  • Specimens past stability
Methodology
Mechanical Clot Detection
Reference Intervals
SexAgeReference IntervalUnit
FemaleAll Age Groups0-8.0sec
MaleAll Age Groups0-8.0sec
Performing Location
Roble Road Core Laboratory
Alternate Names
  • Hexagonal Phase Phospholipid Neutralization
  • Staclot LA
Testing Schedule
Routine, 2 times per week