Test Directory

Test Code
10491
Test Name
Histopathology, Medical Renal Biopsy, Direct Immunofluorescence, Electron Microscopy
CPT Codes
88348
Included Tests
  • Histopathological and Electron Microscopic Evaluation performed by Board Certified Pathologist.
  • Includes: H&E and Frozen H&E

Immunofluorescence Stains -

  • Anti-IgG
  • Anti-IgA
  • Anti-IgM
  • Anti-C3
  • Anti-C1q
  • Anti-albumin
  • Anti-fibrinogen
  • Anti-kappa
  • Anti-lambda

Special Stains -

  • PAS
  • Trichrome
  • Jones
  • Congo Red (if applicable)

Electron Microscopy

Expected Turnaround Time
5 - 10 days
Clinical Utility
  • To obtain a diagnosis; this may be used by the treating physicians to direct appropriate patient management and treatment.
Specimen and Container Info

Alternate Specimen:

Min. Volume External: Medical Kidneys will require three biopsies:

(Kidney kits are available from the Pathology Gross Rooms)

  • One core biopsy in 10% Formalin (for paraffin embedded tissue)
  • One core biopsy in Glutaraldehyde or Karnovsky's Fixative (for Electron Microscopy)
  • One core biopsy in Zeus (or Michel's) Solution (for Immunofluorescence)

Volume External:

Alternate Container:

Collection Instructions

Container:

Medical Kidney kits are available from the Pathology Gross Rooms and contain:

  • one vial of 10% formalin
  • one vial of Gluteraldehyde or Karnovsky's fixative
  • one vial of Zeus fixative solution.

Collect:

  • Place specimen cores immediately in the appropriate solution and/or fixative and transport kit to the Pathology Gross Room.
  • If unable to transport kit immediately to Pathology, refrigerate kit until transport is facilitated.
Processing and Submission Instructions
  • Submit specimen with an EPIC order, Tissue Pathology Requisition Form (HNL-31), or one of the Laboratory's Electronic Forms.
  • Submit the additional form (Renal Biopsy Patient Information Sheet) included in the biopsy kit for Medical Kidney specimens.
  • Clinical history and laboratory findings are essential to interpretation and should be noted on the form(s).
  • Consult the Pathology Department Gross Rooms at 610-402-8163 (LVHN-CC), 484-884-2258 (LVHN-M) or 610-969-2516 (LVHN-17) prior to beginning the procedure for specific instructions, if needed.
Stability Requirements

Refrigerated

  • If unable to transport kit immediately to Pathology, please refrigerate kit until transport is facilitated.
Methodology
Histopathology
Performing Location
Roble Road Core Laboratory
Testing Schedule
Routine, Monday - Friday no holidays