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Test Code
HPAB
Test Name
Histoplasma Species Antibodies
CPT Codes
86698
Included Tests
  • Antibody titers for mycelial and yeast antigens of Histoplasma
Expected Turnaround Time
2 - 4 days
Clinical Utility

Immunodiffusion test is used to detect antibodies to Histoplasma capsulatum. The antigen used is a culture filtrate. Histoplasmin H and M preciptins can be identified by the assay. The M band often appears first and may occur without the H band. M preciptin is found in about 70% of both acute and chronic histoplasmosis cases. Both M and H occur together in only about 10% of patients. Results should be interpreted in the context of clinical presentation and other laboratory findings (e.g., fungal culture).
Specimen and Container Info

Specimen Type: Serum

  

Collection Container: Gold Top, Serum Separator

Alternate Collection Container: Red Top, Plain

Desired Specimen Volume: 0.6 mL
Collection Instructions
  1. Collect a gold top, serum separator tube via venipuncture.
Processing and Submission Instructions
  1. Separate serum from cells.
  2. Transfer 0.6 mL of serum to a clear aliquot tube (screw cap).
Transport Instructions

Transport to the laboratory refrigerated. 
Stability Requirements

Refrigerated

14 days

Frozen

14 days

Freeze/Thaw Cycles

 Stable x2
Causes for Rejection
  • Hemolysis
  • Lipemia
  • Gross bacterial contamination
Methodology
Immunodiffusion
Reference Intervals

See patient report.
Limitations

Negative fungal serology does not rule out the possibility of current infection.
Alternate Names
  • Histoplasma Antibodies, Quantitative, DID
Reference Lab
Labcorp Of America Holdings
Testing Schedule
Monday-Friday
The American Medical Association (AMA) Current Procedural Terminology (CPT) codes published by HNL Lab Medicine are guidelines and are intended for informational purposes only. CPT coding is the exclusive responsibility of the billing entity. View the Terms.
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