Test Directory
| Test Code | ||||
| HYRAP | ||||
| Test Name | ||||
| Hu Yo Ri Antibodies with Reflex to Western Blot and Titer | ||||
| CPT Codes | ||||
| 86255 X 3 | ||||
| Included Tests | ||||
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| Expected Turnaround Time | ||||
| 3 - 7 days | ||||
| Clinical Utility | ||||
| Hu, Yo, and Ri Antibodies with Reflex to Titers and Western Blot - Hu anti-neuronal nuclear antibody (anti-Hu) is found in 5-10% of patients with small cell carcinoma of the lung. Purkinje cell (Yo) antibody is found in patients with paraneoplastic cerebellar degeneration and is associated with breast, ovarian, and other gynecologic cancers. Some patients with ovarian cancer have low titers of Yo antibodies in the absence of cerebellar degeneration. Anti-Hu antibodies are associated with paraneoplastic encephalomyelitis and sensory neuropathy. Anti-Ri antibody can be detected in patients with paraneoplastic opsoclonus/myoclonus syndrome. Neoplasms most often associated with anti-Ri include breast cancer, small cell lung cancer, and gynecological cancers. | ||||
| Specimen and Container Info | ||||
|
Specimen Type: Serum
Collection Container: Gold Top, Serum Separator Desired Specimen Volume: 1.5 mL |
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| Collection Instructions | ||||
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| Processing and Submission Instructions | ||||
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| Patient Preparation | ||||
| Overnight fasting is preferred. | ||||
| Transport Instructions | ||||
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Transport to the laboratory refrigerated. |
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| Stability Requirements | ||||
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| Methodology | ||||
| Immunofluorescence Assay | ||||
| Reference Intervals | ||||
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See patient report. |
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| Reference Lab | ||||
| Quest Diagnostics Nichols Institute | ||||
| Testing Schedule | ||||
| Routine, 3 times per week | ||||
The American Medical Association (AMA) Current Procedural Terminology (CPT) codes published by HNL Lab Medicine are guidelines and are intended for informational purposes only. CPT coding is the exclusive responsibility of the billing entity. View the Terms.
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