Test Directory

Test Code
IGM
Test Name
Immunoglobulin M
CPT Codes
82784
Expected Turnaround Time
1 - 3 days
Clinical Utility

Immunoglobulin M (IgM) is the most primitive and least specialized immunoglobulin and the only one that a neonate synthesizes. In adult serum, it accounts for 5 to 10 percent of the total circulating immunoglobulins. It is not transported across the placenta and is an efficient complement activator.

Specimen and Container Info

Preferred Specimen Type: Serum

Desired Specimen Volume: 2 mL

Preferred Collection Container: Gold Top, Serum Separator

Processing and Submission Instructions

Separator tubes: Contains clot activator and gel for separating serum from cells, but not anticoagulant. Separate serum from cells as soon as the clot has formed (30 minutes). If specimen is centrifuged before clotting is complete, a fibrin clot will form on top of the cell. This may cause the gel barrier to not be intact and could cause improper separation of serum and cells, possibly affecting test results.

Transport Instructions

Transport refrigerated.

Stability Requirements

Refrigerated

7 days

Frozen

<20°C for long-term storage.   

Freeze/Thaw Cycles

Avoid multiple freeze/thaw cycles. 

Methodology
Turbidimetric
Reference Intervals

Age 

IgM mg/dL

0 - 14 days

3 - 35

15 days - 13 weeks

12 - 71

13 weeks - 1 year

16 - 86

Male 1 - 19 years

39 - 151

Female 1 - 19 years

40 - 186

Adult Male

40 - 248

Adult Female

34 - 214

Performing Location
Roble Road Core Laboratory
Testing Schedule
Routine, 6 times per week