Test Directory

Test Code
JIPCR
Test Name
Joint Infection Panel, PCR
CPT Codes
87627
Included Tests

Gram Positive Bacteria

  • Anaerococcus prevotti/vaginalis
  • Clostridium perfringens
  • Cutibacterium avidum/granulosum
  • Enterococcus faecalis
  • Enterococcus faecium
  • Finegoldia magna
  • Parvimonas micro
  • Peptoniphilus spp.
  • Peptostreptococcus anaerobius
  • Staphylococcus aureus
  • Staphylococcus lugdunensis
  • Streptococcus spp.
  • S. agalactiae
  • S. pneumoniae
  • S. pyogenes

Gram Negative Bacteria

  • Bacteroides fragilis
  • Citrobacter spp.
  • Enterobacter cloacae complex
  • Escherichia coli
  • Haemophilus influenzae
  • Kingella kingae
  • Klebsiella aerogenes
  • Klebsiella pneumoniae group
  • Morganella morganii
  • Neisseria gonorrhoeae
  • Proteus spp.
  • Pseudomonas aeruginosa
  • Salmonella spp.
  • Serratia marcescens

Resistance Genes

Carbapenemases

  • IMP
  • KPC
  • NDM
  • Oxa-48-like
  • VIM

ESBL

  • CTX-M

Methicillin Resistance

  • mecA/C and MREJ

Vancomycin Resistance

  • vanA/B

Yeast

  • Candida spp.
  • Candida albicans
Expected Turnaround Time
1 day
Clinical Utility

This panel has been demonstrated to aid in clinical decision making with the rapid detection of fastidious organisms and the ability to identify common resistance markers to begin prompt, appropriate treatment. The panel is not all inclusive for all causes of joint infection. Particularly notable are the absence of coagulase negative Staphylococcus (apart from S. lugdunensis) and Cutibacterium acnes. These organisms were excluded as they can be common contaminants. This panel should be used in conjunction with routine culture methods.

Specimen and Container Info

Specimen: synovial Fluid 

Collection Container: Sterile Container

Desired Volume: 1 mL

Minimum Acceptable Volume: 0.5 mL 

Note: At least 1 mL of synovial fluid is recommended so that synovial fluid analysis and culture can also be performed. Culture must also be ordered for off panel targets and for performance of antimicrobial susceptibility for all organisms. 

Transport Instructions

 Transport to the laboratory at room temperature.

Stability Requirements

Room Temperature

12 hours

Refrigerated

7 days
Methodology
Multiplex Polymerase Chain Reaction (PCR)
Performing Location
Roble Road Core Laboratory
Alternate Names
  • BioFire Joint Infection Panel
Testing Schedule
Routine, daily