Test Directory

Test Code
LACMD
Test Name
Lacosamide, Serum
CPT Codes
80235
Expected Turnaround Time
1 - 4 days
Clinical Utility

Useful for monitoring serum concentrations of lacosamide to ensure compliance and appropriate dosing in specific clinical conditions (ie, severe kidney impairment, mild-to-moderate hepatic impairment, and kidney failure).

Specimen and Container Info

Specimen Type: Serum

Preferred Collection Container: Red Top, Plain

Alternate Collection Container: Gold Top, Serum Separator

Desired Specimen Volume: 1 mL

Collection Instructions
  1. Collect specimen immediately before next scheduled dose.
  2. Collect a red top, plain tube via venipuncture.
Processing and Submission Instructions
  1. Separate serum from cells within 2 hours of collection.
  2. Transfer 1 mL of serum to a clear aliquot tube (screw cap).
Transport Instructions

Transport to the laboratory refrigerated. 

Stability Requirements

Room Temperature

28 days

Refrigerated

28 days

Frozen

28 days
Methodology
Liquid Chromatography - Tandem Mass Spectrometry (Lc/Ms/Ms)
Reference Intervals

See patient report.

Limitations

Abnormalities in liver function tests (eg, alanine aminotransferase) have been observed in controlled trials in adult patients with partial-onset seizures who were taking 1 to 3 concomitant antiepileptic drugs.

Alternate Names
  • VIMPAT
Reference Lab
Mayo Clinic Laboratories
Testing Schedule
Routine, Monday - Saturday