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Test Code
LEUPR
Test Name
Leukemia/Lymphoma Profile, Peripheral Blood/Bone Marrow
CPT Codes
88184, 88185 X 26, 88189
Included Tests

Markers Evaluated: CD2, CD3, CD4, CD7, CD8, CD19, CD45, CD10, CD5, CD23, CD20, CD15, CD33, CD14, CD64, CD117, CD34, CD56, CD57, CD16, CD11c, CD38, CD11b, CD13, HLA-DR, Kappa and Lambda

Additional markers may be performed based on hematopathologist review.
Expected Turnaround Time
2 - 4 days
Clinical Utility

Immunophenotyping by flow cytometry distinguishes among various hematopoietic cell populations and determines the degree of expression of a panel of cell surface antigens. This test is used along with morphologic, cytogenetic, and molecular genetic analysis in the identification/classification of hematopoietic neoplasms (leukemia, lymphoma, myelodysplastic disorders, etc.).
Specimen and Container Info

Specimen

Containers

Preferred Volume

Minimum Volume

Peripheral Blood

Lavender Top (EDTA) and Green Top (Sodium Heparin)

5 mL

3 mL

Bone Marrow

Lavender Top (EDTA) and Green Top (Sodium Heparin)

2 mL

1 ml
Collection Instructions

Refrigerated specimens are acceptable but not preferred
Processing and Submission Instructions
  • Because non-viable cells lead to nonspecific monoclonal antibody binding, specimens should be processed as early as possible.
  • Because of the critical nature of bone marrow specimens, the laboratory will attempt to process all bone marrow specimens received, regardless of age with hematopathologist approval.
  • Specimens collected on a Friday should be received in the Flow Cytometry Department by 1600 to ensure same day processing.
Transport Instructions

Transport to the laboratory at room temperature.
Stability Requirements

Room Temperature

 72 hours
Causes for Rejection
  • Frozen specimens
  • Fixed specimens
  • Incorrect collection containers
Methodology
Flow Cytometry
Performing Location
Roble Road Core Laboratory
Alternate Names
  • Leukemia/Lymphoma Profile, Peripheral Blood/Bone Marrow, Flow Cytometry
  • Immunophenotyping Panel for Leukemia/Lymphoma, Peripheral Blood/Bone Marrow
Testing Schedule
Routine, Monday - Friday no holidays
The American Medical Association (AMA) Current Procedural Terminology (CPT) codes published by HNL Lab Medicine are guidelines and are intended for informational purposes only. CPT coding is the exclusive responsibility of the billing entity. View the Terms.
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