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Test Code
LINEZ
Test Name
Linezolid Level
CPT Codes
80299
Expected Turnaround Time
10 business days
Clinical Utility

Linezolid is an oxazolidinone antibiotic used primarily for treating multidrug-resistant Gram-positive infections, including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE) infections. Due to its potential for toxicity and variable pharmacokinetics, therapeutic drug monitoring (TDM) is recommended in certain clinical scenarios.
Specimen and Container Info

Specimen Type: Serum

Collection Container: Red Top, Plain

Desired Specimen Volume: 2 mL
Collection Instructions
  1. Collect a red top, plain tube via venipuncture.
Processing and Submission Instructions

A completed Pharmacokinetics Laboratory Requisition must accompany the sample.

  1. Allow specimen to clot for 30 minutes.
  2. Separate serum from cells immediately after clotting.
  3. Transfer 2 mL of serum to a clear aliquot tube (screw cap).
  4. Use a separate aliquot tube for each test ordered.
Transport Instructions

Transport to the laboratory frozen.
Stability Requirements

Room Temperature

24 hours

Refrigerated

Frozen

-20°C: 7 days

-70°C: Indefinitely

Causes for Rejection
  • Thawed samples for greater than 24 hours
Methodology
HPLC-UV
Reference Intervals

See patient report.
Alternate Names
  • HPLC (Linezolid, Level)
  • LNZL
  • Pharmacokinetics (Linezolid, Level)
Reference Lab
National Jewish Health
Testing Schedule
Monday-Friday
The American Medical Association (AMA) Current Procedural Terminology (CPT) codes published by HNL Lab Medicine are guidelines and are intended for informational purposes only. CPT coding is the exclusive responsibility of the billing entity. View the Terms.
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